Friday, March 14, 2014

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To compare insulin therapy in type 1 diabetic patients treated either with any controlled subcutaneous continuous infusion of insulin (CSII) using lispro insulin or multiple daily injections (MDI) with once daily glargine and lispro with meals, Researchers in Philadelphia, PA, USA They monitored 16 patients with type 1 diabetes using a sensor system hypertrophic cardiomyopathy for continuous glucose monitoring for 3 days to compare the number, duration, timing and severity of hypoglycemic episodes and hiperglucemiant. They realized that enpacients treated with CSII had more hypoglycemic episodes and hyperglycemia with MDI. The glycemic exposure over 150 mg / dl was similar between the two groups. Maintaining the euglicemia, as determined by the average amount of time devoted to glucose hypertrophic cardiomyopathy in the range of 80-140 mg / dl was significantly marginally better for the inhaler hypertrophic cardiomyopathy for the CSII group. Although in the CSII group had significantly more episodes hypertrophic cardiomyopathy of hypoglycemic below 60 mg / dl, the average duration of hypoglycemia was not significantly different for the two groups. Also similar rates of nocturnal hypoglycemia. No serious adverse events were reported during the entire duration of the study. The researchers concluded: "The well-controlled type 1 diabetic patients with MDI and have fewer trips hipoglucémiques hypertrophic cardiomyopathy hiperglucemiants hypertrophic cardiomyopathy patients treated with CSII." Patient's perspective is also important considering the significant psychosocial component of insulin therapy. For the full summary, click here. http://www3.interscience.wiley.com/journal/121510120/abstract?CRETRY=1&SRETRY=0 International Journal of Clinical Practice Nov 11. 2008 Volume 62 Issue 12, Pages 1858 -1863 2008 Blackwell Publishing Ltd.
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