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A team of researchers has developed a strategy to hunt for the first time the genetic evolution and transmission of MRSA, the antibiotic-resistant Staphylococcus aureus responsible for the majority of nosocomial infections, according to research published Thursday.
These researchers have used new technologies for sequencing the genome of these pathogens to compare strains isolated from different inpatients and extremely accurately determine their genetic relatedness hypertension and how they are transmitted.
The emergence of this mutant staph is the generalization of antibiotics, which corroborates the theory hypertension that excessive use of these anti-infective caused a mutation hypertension of pathogens to resist.
"We wanted to test our method to see if it possible to track the spread of infection by different strains of MRSA from one continent to another as well as small scale between patients of the same hospital," says Dr. Simon Harris, the British Wellcome Trust Sanger Institute, hypertension co-author of this work published in the U.S. journal hypertension Science on January 22.
The new sequencing technology to quickly detect the smallest genetic variations hypertension between these strains and to determine the rate of mutation of their DNA, giving an unprecedented lighting and near real time the evolution of the staphylococci.
For their work, they sequenced the genome of MRSA from samples collected by hospitals in North and South America, Europe, Australia and Asia over the last thirty years. staphylococci
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